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Beyotime
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Servicebio Inc
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Fisher Scientific
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Image Search Results
Journal: Journal of orthopaedic surgery and research
Article Title: Obacunone acts as a histone deacetylase 1 inhibitor to limit p38MAPK signaling and alleviate osteoarthritis progression.
doi: 10.1186/s13018-025-05804-1
Figure Lengend Snippet: Fig. 1 Obacunone (OB) ameliorates cartilage lesions in rat with ACLT-induced OA. A Safranin O-fast green (Top) and HE staining (Bottom) assays were performed to detect the structural integrity of the articular cartilage in ACLT rats administrated with 2.5, 5, or 10 mg/kg OB. Scale bar = 50 µm. B OARSI score was used to evaluate the articular cartilage based on the results of Safranin O-fast green staining. C The level of COMP in rat serum was measured for the detection of articular cartilage. n = 6. Data were analyzed by one-way ANOVA followed by Tukey’s post hoc test. *P<0.05 and ***P<0.001
Article Snippet: Tissue samples were sliced to 4 μm thickness and stained using a Safranin O and
Techniques: Staining